Owner Larry Bennett says keeping his patrons safe weighs heavy on his mind. The gunman targeted a gay night club.
PHOTOS: Mass casualties in Orlando nightclub shooting
"People are a lot more observant. In our case, we will check bags of anyone coming into our bar," said Bennett.
Recent terror attacks in Europe have also hit vulnerable places like bars and restaurants, that retire San Francisco Police Chief Tony Ribera says are hard to protect.
"Soft targets are very tempting to people who want to do harm," said Ribera.
READ MORE: Orlando mayor: 50 dead in nightclub shooting
He says law enforcement needs to have a rapid response and establishments must train employees for emergencies.
People at the Lookout say it was more important than ever to come out and show solidarity with the LGBT community.
"We have to celebrate what we have and we have come so far in the struggle," said Booby Ojha, who came to the club.
"They want us to feel threatened and I want to reaffirm the fact we are going to go on with our lives and we're doing what we want to do."
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The Lookout even has a drink special dedicated to Orlando - jello shots, with money going directly to the city's LGBT community.
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RELATED: Social media reaction to tragedy in Orlando
Click here for full coverage on the deadly mass shooting in Orlando.
A GoFundMe account has been set up for the victims and families of the mass shooting in Orlando, click here for more information.
Flag outside @LookoutSF lowered to half staff. Honoring victims of #OrlandoShooting. #abc7now pic.twitter.com/lnVRtvP5np
— Elissa Harrington (@EHarringtonNews) June 13, 2016
Donations and Jell-O shot money from @LookoutSF will be sent to #OrlandoShooting LGBT community #abc7now pic.twitter.com/qAPphOu8ZK
— Elissa Harrington (@EHarringtonNews) June 12, 2016
The candlelight vigil honoring victims of the #OrlandoShooting has turned into a march to San Francisco City Hall. pic.twitter.com/8ySbw3GCMJ
— Sergio Quintana (@svqjournalist) June 13, 2016
Profound tragedies like this leave us numb & speechless. But we resolve that love, strength & unity will triumph over hate, fear & violence.
— Edwin Lee (@mayoredlee) June 12, 2016
Our prayers are with families & friends of the victims of the Orlando attack & LGBT community. pic.twitter.com/F7iMsoGBGY
— Edwin Lee (@mayoredlee) June 12, 2016
"Thoughts and prayers are not enough." Pres. Obama speaks on mass shootings over the years: https://t.co/Z9gVKrT6Schttps://t.co/WB9P3QCxe6
— ABC7 News (@abc7newsBayArea) June 12, 2016
Florida Gov. Scott: "This is clearly an act of terrorism." https://t.co/ZdaJMtkE0q https://t.co/iTWOMZBjUJ
— ABC News (@ABC) June 12, 2016
FL Gov. Rick Scott: "For anybody that thinks they should do this...law enforcement will be swift in their justice." https://t.co/KarRXJELU9
— ABC News (@ABC) June 12, 2016
.@BrianRoss: Suspected Orlando shooter reportedly unstable, violent toward ex-wife https://t.co/NQJ6Z5aael https://t.co/ufVmtuC1Sg
— ABC News Politics (@ABCPolitics) June 12, 2016
Pulse shooting: In hail of gunfire in which suspect was killed, OPD officer was hit. Kevlar helmet saved his life. pic.twitter.com/MAb0jGi7r4
— Orlando Police (@OrlandoPolice) June 12, 2016
My prayers are with the victims’ families & all those affected by the shooting in Orlando. We will devote every resource available to assist
— Rick Scott (@FLGovScott) June 12, 2016
JUST IN: President Obama has been briefed on Orlando nightclub shooting, White House says. pic.twitter.com/aJEBni7Kus
— ABC News (@ABC) June 12, 2016