Vatrano's goals increased his team lead to 11 and gave him three multigoal games to go along with hat tricks Oct. 15 at home against Carolina and Oct. 28 at Pittsburgh.
"I'm just trying to put the puck in the net and play hard every single night and usually when you play the right way, goals and points come," Vatrano said. "It's early in the season and you just have to keep building game after game."
San Jose dropped to 0-7 on the road and has totaled four goals away from home. The Sharks gave up a pair of goals on five Ducks power-play chances.
"You just can't take some of those penalties," Sharks coach David Quinn said. "We were a little bit short-handed up front today. After not taking any (penalties) against Vegas (on Friday), we took a couple of bad ones tonight that cost us."
Vatrano's initial goal gave the Ducks a 1-0 lead 4:49 into the game when he tipped a blast from Ilya Lyubushkin, sending the puck through the legs of Blackwood.
Kunin tied it with 6:55 remaining in the opening period. Tomas Hertl took a shot from close range that was saved by Gibson, with Kunin cleaning up the loose puck for his second of the season.
Vatrano put the Ducks back on top again with 1:38 left in the first when he fired a one-time blast off a pass from Cam Fowler and scored from the top of the right circle on the power play.
Anaheim delivered again on the power play at with 1:52 left in the third for a 3-1 advantage. McTavish charged the Sharks' goal and flipped a shot past Blackwood off a pass from rookie Leo Carlsson for his seventh of the season.
Anaheim has 10 power-play goals in its last seven games.
"When the game starts you gave to see what's in front of you and make the play," Vatrano said. "I think that's just playing simple on the power play and making the plays we know that we need to make."
Just 49 seconds later the Ducks took a 4-1 lead when Gudas fired a shot from the right point. The puck deflected high in the air off the stick of San Jose's Mike Hoffman and over Blackwood and into the Sharks' goal for Gudas' second of the season.
"It's early in the season but I think we are making steps in the right direction," Gudas said. "We're doing a lot of good things out there. We're staying defensive in a lot of situations and as the season continues it's going to work in our favor that we're in good spots in the D-zone. We're playing right most of the time."
The Sharks were 0 for 2 on their own power-play chances.
"We just don't have a work ethic on our power play right now," Quinn said. "You have to work at it. You just can't say, 'We have five and they have four.' That's not how this works. We're just not getting anything out of it right now."
Sharks: Host Florida on Tuesday night.
Ducks: At Nashville on Tuesday night.
AP NHL: https://www.apnews.com/hub/NHL