She started swimming at 11:16 p.m. Friday and completed the 30-mile swim in a just over 17 hours, arriving to a group of friends and supporters.
On the boat with Chambers was Simon Dominguez, her training partner, who attempted the swim last week but fell short by three miles because of a shark.
She began swimming at 11:16 p.m. Friday.
Four men have completed the Farallon Islands to Golden Gate swim.
Last month, Chambers posted a video on Vimeo of her swimming in the Farallones, which is a 30-mile stretch of water.