The crash was reported at 5:55 a.m. just west of Hopyard Road, according to the CHP.
At least three vehicles caught fire in the collision and one person was killed, CHP officials said.
Multiple lanes were closed following the crash, prompting the CHP to allow all drivers to use the express lane on the highway. All lanes reopened as of 9:07 a.m.
Major delays WB 580 into Pleasanton. Fatal ACC 4 lanes blocked and motorcycle down in left lane in back up. pic.twitter.com/U3hgSIiZw4— SueHallTraffic (@SueHallTraffic) April 27, 2016