Dillon Brooks added 12 points for Memphis. Ziaire Williams and Brandon Clarke had 11 apiece and De'Anthony Melton 10. Steven Adams had 13 rebounds, six offensive.
The Grizzlies never trailed, turning in their best performance of this series to pull to 3-2 even with All-Star guard Ja Morant sitting out his second straight game because of a bone bruise in his right knee. They improved to 4-11 when facing elimination.
Memphis scored 77 points in the first half, the most in franchise postseason history. The Grizzlies pushed their lead to 55 in the third quarter, threatening the three biggest postseason blowouts in NBA history. Their 52-point lead after three tied for the largest in a playoff game in the past 70 years.
When Memphis fans chanted "Whoop That Trick! Whoop That Trick!" early in the fourth, Stephen Curry laughed on the court laughing while Draymond Green swung a towel in unison with the crowd.
Game 6 is Friday night in San Francisco, where the Warriors have won five straight playoff games and their last seven overall.
Klay Thompson led Golden State with 19 points, Jonathan Kuminga added 17, Curry had 14 and Damion Lee and Moses Moody each had 10.
The Warriors lost for the first time with assistant Mike Brown filling in for coach Steve Kerr, who missed his second straight game since testing positive for COVID before Game 4.
The Grizzlies got back to doing the things that helped the post the second-best record during the regular season. They outrebounded Golden State and dominated on the offensive boards. They forced plenty of turnovers and got their best production from the bench of this series.
Golden State, thanks to Poole coming off the bench, had outscored Memphis' reserves each of the first four games. Facing elimination, the Grizzlies had a 28-8 edge through the first two quarters and finished with a 52-35 margin.
Memphis led 38-28 at the end of the first quarter and continued a 24-8 run into the second quarter to go up 53-36t. They finished the second on a 20-4 run, including 14 straight, to outscore Golden State 39-22 for a 77-50 lead at halftime.
Then the Grizzlies opened the third quarter outscoring Golden State 20-6, prompting fans to start chanting "Whoop That Trick." Memphis just pushing, outscoring Golden State 42-17 in the third for a 119-67 lead going into the fourth.
Brown benched most of his starters by 3:44 of the third, and Memphis coach Taylor Jenkins followed to start the fourth resting up for a flight to California and Game 6.
Warriors: The 77 points allowed in the first half matched the most allowed all season. They also gave up 77 on Jan. 13 at Milwaukee. ... The Warriors also fell to 12-4 in Game 5s since 2015. ... Nemanja Bjelica started the third quarter in place of Jonathan Kuminga. Bjelica had played only four minutes in this series. ... Otto Porter Jr. played 12 minutes before being sidelined by a sore right foot.
Grizzlies: They matched their most first-half points, also scoring 77 against New Orleans on March 8. They did it by outscoring Golden State 24-5 on second-chance points with a 18-4 edge on the offensive boards.
The Bucks also led Philadelphia by 52 (124-72) on March 30, 1970. Denver beat New Orleans by 58 on April 27, 2009, matching the margin Minneapolis beat St. Louis on March 19, 1956. Golden State beat the Los Angeles Lakers by 56 on April 21, 1973.
Memphis scored 25 points off turnovers in the first half - most by any team in the 1st half over the last 25 postseasons. The Warriors had been averaging 19 turnovers a game in this series and had 14 by halftime and finished with 20.
BROWN'S FIRST LOSS
Brown, the next coach of the Sacramento Kings, had been 12-0 coaching the Warriors in the postseason, winning 11 straight in the 2017 playoffs. He also won Game 4 when the Warriors took the lead for the first time with 45.7 seconds left to pull out a win for a 3-1 series lead.
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