PHOTOS: Explosion reported at Ariana Grande concert in England
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Manchester police say an apparent suicide bomber set off an improvised explosive device at the end of an Ariana Grande concert.
Police raised the death toll to 22 early Tuesday, and dozens more have been reported injured.
Chief Constable Ian Hopkins says forensic investigations are continuing to determine if the attacker had accomplices. He provided no information about the individual who detonated the device.
In a statement on social media Monday night, the Greater Manchester Police say emergency services are responding to the arena.
"There are a number of confirmed fatalities and others injured," police say.
RELATED: 'Everyone was just screaming': Concertgoers describe chaos at Ariana Grande concert
"Please stay away from the area," the Greater Manchester Police said on Twitter.
In another tweet, police say, "Emergency services responding to serious incident at Manchester Arena. Avoid the area."
Social media accounts say a couple loud bangs were heard at the arena where singer Ariana Grande was performing.
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Eyewitness Karen Ford told the BBC, "The lights had come up everyone was just getting out and walking towards the stairs, when all of a sudden this huge sound which sounded like an explosion went off."
She added: "Everyone just stopped and turned around, and then somebody shouted 'it's a bomb' and everyone just started running. Everybody was trying to push people up the stairs. There was a lot of children there without parents. There was no one to calm them down so everyone was just screaming crying and pushing."
RELATED: Performers send messages of prayers after explosion
Andy Holey, an eyewitness, told the BBC that he was waiting outside the concert and was blown over by the force of what he described as an "explosion." When he awoke, he said he saw many casualties around him. He added that it was unclear if they were injured or dead.
Abby Barker, who attended the concert, told ABC News that Grande had just left the stage when there was a loud bang. "I looked across the arena and everyone over there started running in different directions, screaming in panic," she said. "We all started panicking too and ran out the doors and ran down the stairs out of the arena. We got outside and children were crying their eyes out, people talking about it being a bomb/gunshots, there were many parents running towards the arena but no one knew exactly what it was."
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VIDEO: UK police investigate reports of explosion at Ariana Grande concert
VIDEO: UK police investigate reports of explosion at Ariana Grande concert
A representative for Grande reported she is okay.
It is unclear at this time what has happened, but concert-goers reported hearing a loud bang at the end of the concert, and social media posts say people were running out of the arena. Emergency services are on the scene of the incident.
Ambulances were seen outside the arena, and rail service was halted in the area. The nearby Manchester Victioria Rail Station was evacuated due to the incident.
Facebook has activated a safety check for attendees of the event. Click here to view the Facebook page.
Click here for full coverage on the deadly Manchester Arena terror attack.