Police say the explosion happened around 10:15 a.m. in the area of Skyline Drive and Westline Drive and could be heard from miles around.
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Members of the bomb squad spent hours looking over the wreckage - at times pulling out items, including a propane tank.
MORE: New video shows moment San Francisco home exploded, killing 1
New video shows moment San Francisco home exploded, killing 1
"I grew up in England during the IRA terrorist attacks and there was a massive bomb about five miles from my house, and it was the same thing, just a huge 'ka-bang' and jolt," said Helen Nicely.
Once given the all clear, investigators from Daly City Fire, as well as the FBI and the ATF were allowed to get a closer look at the car.
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Home surveillance video captured the explosion rattling the neighborhood.
Glenn Ibarrientos was getting help unloading lumber outside his home when he heard the explosion from blocks away.
"It was loud, I mean people heard it all the way up the block, everyone just went out at the same time - our neighbor said 'what was that, was that an earthquake?" Ibarrientos said.
To residents, it's still a mystery what exactly caused the blast.
"It's kind of weird, why you would have a propane tank in a car like that sitting there. It's not hot temperatures, you're trying to think of what things can detonate a propane tank," Ibarrientos said.
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Police say no one was in the car when it exploded.
At this point, there also doesn't appear to be any other damage from the blast.