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Moore said at a late-afternoon news conference that about 700 people were arrested Sunday during mass protests over Floyd's death and police brutality. He noted that about 10% of those arrests were for burglary or looting, saying, "We didn't have protests last night, we had criminal acts.''
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"We didn't have people mourning the death of this man, George Floyd, we had people capitalizing. His death is on their hands as much as it is those officers,'' Moore said.
He apologized minutes later, saying he "misspoke when I said his blood is on their hands'' and that he regretted "that characterization.''
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Moore went on to say that he did not regret nor would he apologize to the people "committing violence, destroying lives and livelihoods and creating this destruction.''
Of Floyd, he said, "His memory deserves reform. His memory deserves a better Los Angeles, a better United States and a better world.''
On Monday night, he tweeted, "I misspoke when making a statement about those engaging in violent acts following the murder of George Floyd.''
There were many tweets calling for Moore's resignation, interspersed with an occasional statement of support for the police chief.
Around 11 p.m., Moore issued an official apology in which he said, "I recognize that my initial words were terribly offensive. Looting is wrong, but it is not the equivalent of murder and I did not mean to equate the two. I deeply regret and humbly apologize for my characterization. Let me be clear: the police officers involved were responsible for the death of Mr. George Floyd.''
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Mayor Eric Garcetti issued a statement on Twitter, in which many also called for Moore's resignation, and some calling on Garcetti to fire the police chief.
Take a look at the latest stories and videos about the investigation into George Floyd's death in Minneapolis and protests across the U.S.
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City News Service contributed to this report.