El Cerrito police identified the men as 34-year-old Patrick Scheckells from Oakland and 56-year-old Andre Alberty from San Francisco.
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Police say officers started chasing the men's pickup truck after a burglary at a tobacco shop in San Pablo.
RELATED: El Cerrito chase, fatal crash near Bay Bridge raising safety concerns over police pursuits
Police say that right after they called off the chase on eastbound I-80, the men made a U-turn and started driving the wrong-way on westbound I-580 where they slammed into a car and killed 57-year-old David Lee Weiner.
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Both men face multiple federal charges.