The fiery crash happened around 11 a.m. and briefly shut down all eastbound lanes near Fruitvale Avenue in Oakland, authorities say.
Police say an SUV collided with a Chevy Volt.
MORE: Authorities investigating deadly overnight Bay Area crashes
The SUV burst into flames-- catching fire to some shrubs and trees. The SUV driver escaped without injury.
The victim in the Chevy Volt was taken to Highland Hospital in Oakland where she later died from her injuries.
Her identity has not been released.
If you're on the ABC7 News app, click here to watch live