The Weeknd, Florence and the Machine, and Janet Jackson are headlining the three-day music festival.
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On Thursday organizers put the finishing touches on the venue, which this year includes a new "Grasslands" area that celebrates cannabis.
There are also some new safety features every attendee needs to know about.
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"We're really only letting clear bags through our gates here. If you have a small purse or a fanny pack or something like that, that's OK," said Rick Farman, a co-producer of the event.
Now in its 11th year, the festival also showcases local restaurants, wineries and breweries, along with local art, comedy and a series of speakers.
Click here for more about the event. And to listen to a live stream of select sets from the event between Aug. 10 to Aug. 12, check out the Outside Lands Radio channel.