The suspects were driving at speeds up to 110mph on I-580.
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The police chase started on the freeway. Then the driver crashed into a car and both suspects exited on foot and onto the streets of Oakland. At one point, they were seen running just across the street from the Rene C. Davidson courthouse.
It appears police are currently surrounding a building in the area of Jackson and 11th streets.
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Stay with ABC7 News for updates on this developing story.