Seven-thousand runners from 48 states and 44 countries will race across the Golden Gate Bridge and on city streets.
Local bands will also perform live on the race route along the Marina.
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Drivers beware, while the race itself is set to run from 6 a.m. to 11:30 a.m., road closures vary throughout the day.
Some went into effect Saturday and most reopen by midday on Sunday.
Get full details about the Rock 'n' Roll Half Marathon course map and road closures here.