Video taken by ABC7 Mornings anchor Reggie Aqui shows the front of the Walgreen's on 23rd and Mission entirely broken open with a smashed ATM sitting right outside.
SFPD says it happened before sunrise on Sunday.
MORE: Final day of business for 2 more SF Walgreens stores, another will close later this week
Final day of business for 2 more SF Walgreens stores, another will close later this week
Officers say they chased two vehicles with several suspects inside, but lost track of them.
MORE: Thief steals garbage bag full of items from SF Walgreens with security filming in plain sight
Out-in-the-open theft at SF Walgreens caught on video
They say the same suspects also burglarized a nearby gas station right before.
Aqui says this is the last Walgreens store open in the Mission district. There were previously three locations.
Anyone with information is asked San Francisco police at 415-575-4444.
If you're on the ABC7 News app, click here to watch live