The CHP initially received a report around 11:05 a.m. of someone driving west in the eastbound lanes of Highway 4 near Railroad Avenue. The vehicle, a Dodge Durango, collided head-on into a Honda Accord, and a Toyota and a tanker truck then hit the Honda. The Dodge driver fled but was taken into custody by Pittsburg police, CHP officials said.
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The Honda driver died at the scene of the collision and a passenger in the car was taken to a hospital with major injuries. The Toyota driver and an infant passenger were also taken to the hospital, while the tanker truck driver did not report any injuries, according to the CHP.
MORE: 5 victims, including 3 kids under 10 years old, identified in deadly wrong-way Pittsburg crash
The name of the Dodge driver under arrest and the Honda driver who died in the crash were both not immediately available.
Investigators believe impairment may have been a factor in the crash, which blocked lanes of eastbound Highway 4 until shortly after 2 p.m.
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Anyone with information about the case is asked to call the CHP's Contra Costa-area office at (925) 646-4980.
This is the second wrong-way crash in the Pittsburg area on Highway 4 in a month. In November, five people were killed, including three children in a wrong-way crash.