The crash occurred around 5 a.m. between a bus and multiple vehicles.
Metering lights were turned on shortly after the crash and traffic was backed up for miles past the MacArthur Maze.
Injuries were reported but officials have not released details on how severe.
All lanes were reopened by 7:30 a.m.
Before you head out to your car, be sure to check out the ABC7 traffic maps for real-time information to help you navigate through traffic jams.