What to know about delta and other COVID-19 variants of concern
Experts weigh in on what we know now about the delta variant and more
The Centers for Disease Control and Prevention listed the COVID-19 delta variant as one of its "variants of concern" (VOCs) on June 15. According to the CDC, VOCs can be more contagious, more dangerous, less susceptible to available treatments or harder to detect.
The current VOCs all have mutations in the virus's spike protein, which acts as a key to break into cells to infect them. And that's a potential concern because the spike protein from the original version of the virus is what scientists used to design all three authorized vaccines. It's also what monoclonal antibody treatments latch on to so the virus can't get into your cells, effectively "neutralizing" the threat. So far none of these mutations have changed the virus enough to undercut the vaccines.
The uncontrolled spread of SARS-CoV-2, the virus that causes COVID-19, means the virus is mutating quickly. That's why many new variants are being discovered in places with the highest infection rates and large numbers of unvaccinated individuals, like the United States, the United Kingdom, India and Brazil.
"Viruses mutate; they change their form all the time," said ABC News medical contributor, Dr. Simone Wildes, a board-certified infectious disease physician and public health expert at South Shore Health in Weymouth, Massachusetts.
"We're not just dealing with one virus, we're dealing with a lot of viruses. Because there's been uncontrolled replication around the world for the last year and a half, we've created variants beyond variants," said Dr. Todd Ellerin, ABC News medical contributor and Director of Infectious Diseases at South Shore Health.
Thousands of variants exist around the world, but most of them do not change the way the virus acts. Experts are constantly working to figure out which variants we should focus on and how they change how we combat COVID-19. Right now, there are only a handful of concerning COVID-19 variants.
Alpha variant (B.1.1.7)
The alpha variant was first identified in the U.K. and thought to have emerged in September 2020. It spread in Europe before arriving in the U.S. in December 2020 and was the dominant viral strain in American until early June this year.
Compared to the original Wuhan strain, the alpha variant is about 50% more contagious and led to an increase in hospitalizations and deaths in the U.K. However, the alpha variant is susceptible to available vaccines, according to the CDC. Treatments called monoclonal antibodies, which are designed specifically to combat the virus, also still work against the alpha variant.
