SFPD says the shooting happened just before 11 p.m. Sunday at Grant and Columbus Avenues.
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Police said Monday afternoon a 23-year-old man from Solano County was shot and pronounced deceased at the scene.
Two 24-year-old men from Sacramento County, a 22-year-old man from Alameda County and a 20-year-old woman from Contra Costa County were wounded and taken to a hospital, police said. Their wounds were all said not to be life-threatening.
ABC7 News talked to several witnesses in surrounding businesses, who describe hearing between 4 and 6 gunshots- then coming out to find at least two victims.
As of 4:45 a.m., police have cleared the scene, but a portion of Columbus was shut down overnight and there was police tape outside of Condor Club at 560 Broadway.
Employees there emphasize the shooting did not happen at the club - rather, they say workers rushed outside and stepped in to help after hearing the shots.
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There were no immediate arrests.
Police said the shooting was believed to be an isolated incident and not random, but they did not give further details and the investigation was ongoing.
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Police are asking anyone with information to contact them at 415-575-4444.
Video is from an earlier update
The Associated Press contributed to this article.