Wednesday's concert will be the first of four sold-out performances at the downtown Los Angeles venue.
Fans, also known as the "BTS Army," with general admission floor tickets have been lined up for days down the street and around the block for the much-anticipated kick-off. The boy band tweeted about the fans seen on ABC7's live report and asked them to "wait a little bit longer."
BTS is a seven-member K-pop group from South Korea that has morphed into a global phenomenon.
VIDEO: South Korean boy band BTS makes history with top spot on Billboard 200
The boy band recently celebrated their 5th anniversary.
VIDEO: TS fans in SoCal celebrate South Korean boy band's 5th anniversary
The band's latest single, "Idol," knocked Taylor Swift off the record books to earn the highest 24-hour music video debut in YouTube history, with more than 45 million views on the first day.
"Something about them just kind of spoke to me," said fan Daniela Rios. "It's just something about their music and the message they like to put out that is really encouraging for people my age and people that are younger than me."
In 2017, BTS was the most tweeted about celebrity, with more than 5 million likes or retweets -- that's more than President Donald Trump and Justin Bieber combined.
Three other concerts are expected to take place at Staples Center through Sunday night. For more information, click here.
BTS will also be in Oakland on Sept. 12 at 8 p.m. Click here for details on tickets.