The warning is in effect from 11 p.m. Friday until 8 a.m. Saturday, according to ABC7 Meteorologist Mike Nicco.
MORE: 'Lucky so far': CA experienced less wildfire activity this fall
"Though it's a small window, it's when most of us will be sleeping, so you need to be ready just in case," he said.
Just over a year ago, the Caldor Fire destroyed more than 1,000 homes and threatened South Lake Tahoe.
The Fire Weather Watch is a result of a long stretch of warm and dry weather. After the weekend, the cold front will bring in a wintry mix.
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