Dr. Kevin Mack, 52, was killed in the crash at the intersection of Octavia Boulevard and Oak Street at about 6:20 a.m. Thursday.
Mack and about 15 other people were riding the shuttle to San Francisco General Hospital when it collided with the big-rig traveling north on Octavia Boulevard, police said.
Mack was ejected in the crash and landed underneath the big-rig, which was carrying several cars. He was pronounced dead at the scene.
Witness reports indicate the shuttle bus driver may have ran a red light while traveling east on Oak Street before the collision, according to police. The crash remains under investigation.
A viewing for Mack's family and friends will be held at 6 p.m. Tuesday at St. Agnes Catholic Church, located at 1025 Masonic Ave. in San Francisco. His funeral mass will be held at the same location at 10 a.m. Wednesday.
UCSF is also holding a memorial service for Mack this Thursday at Cole Hall, located at 513 Parnassus Ave. on its Parnassus campus.
For people unable to attend, the school will simulcast the service to the San Francisco General Hospital cafeteria and to Room 150 at University of California at Berkeley's University Hall.
In lieu of flowers, donations to benefit Mack's husband and two children, ages 7 and 4, can be made to the Kevin Mack, M.D. Memorial Fund through Wells Fargo Bank.
A website in Mack's memory also has been set up at www.kevinmack.forevermissed.com, where comments have been left from friends, colleagues and students.
"Kevin was an amazing teacher, physician, role model, and friend," Iljie Fitzgerald wrote. "I will miss his joie de vivre, his kindness, and his rare gift of inspiring so many of his students; I feel very, very lucky to have been one of them."
Three other victims, ranging from 58 to 85 years old, also suffered minor injuries in Thursday's crash but are expected to survive.
UCSF officials have placed the shuttle bus driver on paid administrative leave pending an investigation into the crash.