End of the 1st quarter, the 49ers and Seahawks are tied 3-3. Watch the game on ABC7!

San Francisco 49ers safety Dashon Goldson celebrates after recovering a fumble by Buffalo Bills tight end Scott Chandler during the second quarter of an NFL football game, Sunday, Oct. 7, 2012, in San Francisco. (AP Photo/Ben Margot)

October 18, 2012 6:17:24 PM PDT
The NFC West division lead is on the line at Candlestick Park for Thursday Night Football. The 49ers face off against the Seattle Seahawks.

2nd quarter current score: 49ers 3, Seahawks 6

The 49ers, Seahawks, and Arizona are tied for first place -- all with 4-2 records. It's the 49ers first division game of the season. Seattle is coming off a big upset win over the New England Patriots on Sunday, while the Niners will try to rebound from a disappointing home loss to the New York Giants. It will be a tough turnaround for both teams after a short week of preparation.

On ABC7, we're featuring 49ers greats Jerry Rice and Brent Jones and we'll give away $49,000 on "After the Game," with Larry Beil and Mike Shumann.

WR Mario Manningham inactive for 49ers vs. Seattle

Wide receiver Mario Manningham is among the inactives with a shoulder injury for the San Francisco 49ers against the Seattle Seahawks on Thursday night.

Brandon Jacobs is taking Manningham's spot on the active roster for the first time after a left knee injury sidelined the former New York Giants running back since the preseason. Left tackle Joe Staley, who had a concussion in Sunday's 26-3 home loss to the Giants, has been cleared to play and is in San Francisco's starting lineup.

Manningham was injured early against New York last weekend. Randy Moss is listed as a starting wide receiver along with Michael Crabtree.

All of Seattle's starters are active.

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