Officers reported to the area of South Ninth and Reed streets at about 2:45 a.m. after receiving a report of a fight involving multiple males, Sgt. Jason Dwyer said.
The three victims were transported to a hospital with injuries that were not considered to be life threatening.
At about 3:55 a.m., a fourth male victim connected to the fight walked into a hospital with a small laceration, Dwyer said. No arrests were made.
It is unknown whether the brawl was gang related.