The CHP said the collision was first reported at 5:40 a.m. just north of High Street.
At least one person was injured and officers at the scene reported oxygen tanks blocked lanes of the freeway, per the CHP's Traffic Management Center.
The No. 1 and 2 lanes were blocked during the morning commute but have since reopened.
Stay with ABC7 News for the latest details on this developing story.
UPDATE: Two lanes have reopened. SIG ALERT is still in effect. pic.twitter.com/UIu8TxnqEY— Jobina Fortson (@JobinaFortson) December 31, 2019
SIG ALERT: ALL lanes are blocked on NB 880 before Fruitvale due to a two car crash. Injuries have been reported and oxygen tanks are sprawled across the roadway. https://t.co/9gtVKbPyH9 pic.twitter.com/j5po1K7xlG— Jobina Fortson (@JobinaFortson) December 31, 2019