The jurors told Judge Barbara Mallach they deadlocked 7-5 for guilty this afternoon, according to Assistant District Attorney Karen Guidotti. Mallach discharged the jury and declared a mistrial.
On Jan. 12, the district attorney's office will announce whether it will retry the case, Guidotti said.
Prosecutors allege that Orozco, now 19, shot and killed 21-year-old Francisco Rodriguez on July 12, 2005, over a perceived disrespect between rival gangs.
Orozco was 14 at the time of the shooting. In February 2008, he also gained notoriety as the only person to escape San Mateo County Youth Services Center, where he was in custody. Authorities tracked him down in Texas in August 2008.
Orozco and defense attorney Raymond Buenaventura told jurors that another man, Faustino Ayala, killed Rodriguez over gang rivalries and intimidated the younger Orozco into confessing to the crime. Orozco testified that he is not a member of the Sureno street gang.
Jurors heard closing statements from both sides Dec. 4, and began deliberations that same day.