The image, taken from video cameras in the area, shows a white Dodge Durango SUV with a black ski rack on top, as described by witnesses to the collision.
The fatal collision was reported at 11:16 a.m. at Bayshore Boulevard and Visitacion Avenue, police spokesman Officer Albie Esparza said.
The pedestrian, a woman in her 60s, had been walking east on Visitacion Avenue and crossing Bayshore Boulevard in a crosswalk with a green light, Esparza said.
She was struck when an SUV that had been heading east on Visitacion Avenue made a left turn onto Bayshore.
The driver continued north on Bayshore before turning left onto Leland Avenue, a block away, Esparza said.
Witnesses told police it looked like the driver was turning around to head back to the scene, but instead he drove away, south on Bayshore Boulevard, according to Esparza.
The suspect is described as having short curly hair and light brown skin and is either black with light skin or Hispanic, Esparza said.
The woman was pronounced dead at the scene, Esparza said.
She has not yet been identified, according to the San Francisco medical examiner's office.
The collision affected San Francisco Municipal Railway buses and light-rail vehicles Thursday afternoon, with T-Third Street inbound light-rail vehicles switching back at Armstrong Avenue and the 8X-Bayshore Express and 9-San Bruno bus lines rerouting around the area.
And to give you an idea of just how serious this is, San Francisco has recorded six traffic fatalities this year. That is more than the number of homicides in the city.
(ABC7 News contributed to this report)