Police attempted to pull the male driver over for a minor traffic violation when he failed to stop his vehicle and crashed into a fire hydrant and then a building near the intersection of Folsom and Essex Streets at 3:43 a.m.
The suspect was transported to the hospital and taken into custody, police said.
Police are investigating if drugs or alcohol were a factor in the collision.
Water and fire crews are on scene this morning and have closed Essex Street, which is a main access point to the San Francisco Bay Bridge.
