Officers said a male suspect bailed from a vehicle at 3:23 p.m. near the Mariposa Street on- and off-ramps to Interstate Highway 280, near Indiana Street.
Police searched the area for additional suspects and closed the Mariposa Street ramp to Highway 280. Commuters were encouraged to avoid the area due to heavy traffic as a result of police activity.
As of 5:25 p.m., roadways and highway access ramps were being reopened after the conclusion of the search, according to police.
San Francisco police said one of the suspects was wanted in connection with a case in Oakland, but they have not publicly released his identity.
Stay with ABC7 News for the latest details on this developing story.