The collision happened around 1:05 a.m. on northbound state Highway 85 at Evelyn Avenue.
The two-vehicle collision reportedly involved one of the vehicles heading south in the highway's northbound lanes.
One of the vehicles reportedly caught fire, becoming fully engulfed in flames, CHP officials said.
All northbound lanes of the highway were closed around 1:30 a.m. and have since reopened.
Northbound 85 in Mountainview is close to re-opening after fatal collision overnight pic.twitter.com/lZ768NXb5S— Amy Hollyfield (@amyhollyfield) September 13, 2019