The pursuit started at about 12:50 a.m. near the intersection of Martin Luther King Jr. Way and 36th Street, according to CHP Sgt. Trent Cross.
CHP officers chased the silver Mercedes vehicle from northbound Interstate Highway 580 to eastbound state Highway 24 and then off the highway and into Berkeley.
The driver, a 47-year-old Oakland woman, eventually made a turn onto a dead-end street and gave up, Cross said.
The car was not stolen, the suspect had a valid driver's license and she was not under the influence of alcohol, Cross said. However, he said authorities planned to test of she was under the influence of drugs.