A family spokesman says Bochco died Sunday in his sleep after a battle with cancer.
Over a career that spanned more than 50 years in television, Bochco was known as an innovator who created and produced shows that won critical acclaim and made a lasting impact on the network television landscape.
Among the shows he helped create or produce were "Hill Street Blues," "L.A. Law," "Doogie Howser, M.D." and "NYPD Blue."
Video: Steven Bochco discusses his memoir in 2016 interview
Bochco had been diagnosed with a rare form of leukemia years ago and detailed his treatments in his memoir, "Truth is a Total Defense."
In a 2016 interview with Eyewitness News, he explained what led him to launch his producing career with the highly acclaimed "Hill Street Blues" in the early 1980s.
"I just got tired of doing the same stuff over and over again, which is what I had been doing for 15 years," he said.
He also discussed battling the networks over creative control, winning out with decisions such as casting Neil Patrick Harris as Doogie Howser and showing some partial nudity on "NYPD Blue."
During a 15-year span at the height of his creative powers, Bochco's shows won 10 Emmy Awards.
The Associated Press contributed to this report.
Steven Bochco sat with Jake Kasdan and myself before we started Freaks and Geeks and let us grill him for advice. We used all of it. He was a great man and will forever be an inspiration. https://t.co/IWT2Zfr3Nf— Judd Apatow (@JuddApatow) April 2, 2018
It was his vision, style, taste and tenacity that made me love watching TV. It was being on #NYPDBlue that made me love working on TV. Thank you and rest well Steven Bochco. You were one of a kind. https://t.co/jTqhyAuO0k— Sharon Lawrence (@sharonlawrence) April 2, 2018
Steven Bochco Dies at 74 https://t.co/4L1lFXhIJF via @thr This man meant the world to me. Mentor is not a strong enough word. Nor is friend. He taught me so much about the business, and life, and always had my back. I'm so sad.— Reginald Hudlin (@reghud) April 2, 2018
Celebrities and notable figures who have recently passed away