"How many home runs does he have?" Lackey asked sarcastically after the game.
Wednesday was Bethancourt's third of the season, and it was a monster blast to left that landed on the street outside Wrigley Field. Bethancourt watched it for a moment before rounding the bases.
"I got a long memory," said Lackey (4-2), who took the loss after going eight innings and allowing a run on three hits, with no walks and seven strikeouts.
Bethancourt and Lackey don't have a history; this was the first meeting between the hitter and pitcher, which Lackey was well aware of.
"Oh, I know," Lackey said. "He'll learn."
Bethancourt's homer was the lone run of the game, giving the Padres a doubleheader sweep and the Cubs their first two-game losing streak of the season.
Lackey irate with Bethancourt's HR reaction
Christian Bethancourt breaks up John Lackey's perfect game in the fifth inning with a solo home run. Bethancourt took a few strides before taking off for the bases, which didn't sit well with Lackey.
Padres blank Cubs
Drew Pomeranz strikes out 10 and Christian Bethancourt smacks a solo shot in the Padres 1-0 win over the Cubs.