Two California Highway Patrol officers and three Golden Gate personnel are among the injured, a spokesperson said.
Before the rally, one man was arrested by CHP after he tried to stop traffic on the bridge. The man was also charged with resisting arrest.
SKY7 was overhead hundreds of protesters gathered around 3 p.m., not far from the toll plaza at the Golden Gate Bridge welcome center.
ABC7 News Reporter Cornell Barnard talked to some of the protesters.
"I'm advocating for choice in this issue, I don't want people to be forced to put anything in their bodies," said Black Lives Matter advocate Hawk Newsome.
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CHP moved in Thursday evening to stop the protesters from getting on the bridge, closing down at least one lane of northbound traffic.
During the backup, an accident occurred where an SUV collided with a street sweeper pushing it into a line of CHP officers.
VIDEO: 5 injured, including CHP officers, after car crash near anti-vaccine rally at Golden Gate Bridge
At least one of the officers was hurt but it's unknown if there are more injuries.
Around 5 p.m. Golden Gate Bridge officials tweeted that the east sidewalk was closed to pedestrians but open to cyclists. However, the west sidewalk would remain open for both.
EAST SIDEWALK CLOSURE 11/11: For your safety the east sidewalk is now closed to pedestrians. West sidewalk remains open for cyclists. Shuttles are running for pedestrians. Parking lots remain closed.— Golden Gate Bridge (@GGBridge) November 12, 2021
Thank you for your patience.
SKY7 was over the scene when CHP officers put a man in the back of a patrol vehicle. This same person was spotted earlier blocking traffic on the bridge holding up a sign.
The Vista Point parking lot closed early Thursday in anticipation of the protest.