Officers responded to reports of shots fired in the area of Tyler and California streets shortly after 11:30 p.m., police said.
The man was found on the sidewalk and with gunshot wounds, according to police.
Emergency personnel transported the man to a local hospital where he succumbed to his injuries, police said.
Anyone with information regarding the homicide is asked to call the Berkeley Police Department at (510) 981-5741 or (510) 981-5900.