The suspect, who may have been in disguise, entered the bank in the 300 block of Grand Avenue around 11:30 a.m. and gave a teller a note saying he was armed and that he wanted money from the teller drawers, police said.
The teller gave the suspect an undisclosed amount of money, and the suspect then fled from the bank on foot. He was last seen running eastbound from the bank.
No customers or employees were injured during the robbery.
The suspect is described as a Middle Eastern or Hispanic man, about 5 feet 6 inches tall and between 160 to 180 pounds. He was wearing a yellow turban, thick round shaped eyeglasses, a gray long-sleeve button up shirt and dark pants. He had a beard and was carrying a black laptop bag with the strap over his shoulder, police said.
Police said it is unclear if the turban, glasses and beard were real or were part of a disguise.
Of anyone has information regarding this robbery, please contact the South San Francisco police at (650) 877-8900.