Three former presidents joined in the eulogies at Atlanta's Ebenezer Baptist Church after nearly a week of mourning that took the civil rights icon from his birthplace in Alabama to the nation's capital of Washington to his final resting place in his home of Atlanta.
Lewis was "a man of pure joy and unbreakable perseverance," Obama said during a fiery speech in which he hearkened back to Lewis' legacy and connected it to the ongoing fight against those who are "doing their darndest to discourage people from voting."
"He as much as anyone in our history brought this country a little bit closer to our highest ideals," Obama said. "And some day when we do finish that long journey towards freedom, when we do form a more perfect union, whether it's years from now or decades or even if it takes another two centuries, John Lewis will be a founding father of that fuller, fairer, better America."
Former President George W. Bush said Lewis preached the Gospel and lived its ideals, "insisting that hate and fear had to be answered with love and hope." Lewis died July 17 at the age of 80.
Speaker of the House Nancy Pelosi recalled how Lewis' body was lying in state at the U.S. Capitol earlier this week, and a double rainbow appeared.
"There was this double rainbow over the casket," she said. "He was telling us, 'I'm home in heaven, I'm home in heaven.' We always knew he worked on the side of angels, and now he is with them."
The arc of Lewis' legacy of activism was once again tied to Ebenezer's former pastor Martin Luther King Jr., whose sermons Lewis discovered while scanning the radio dial as a 15-year-old boy growing up in then-segregated Alabama.
King continued to inspire Lewis' civil rights work for the next 65 years as he fought segregation during sometimes bloody marches, Greyhound bus "Freedom Rides" across the South and later during his long tenure in the U.S. Congress.
"Get in good trouble, necessary trouble, and help redeem the soul of America," Lewis said of his run-ins with the law. The phrase was repeated several times during the funeral.
PHOTOS: John Lewis through the years
"We will continue to get into good trouble as long as you grant us the breath to do so," one of King's daughters, the Rev. Bernice King, said as she led the congregation in prayer.
"Here lies a true American patriot who risked his life for the hope and promise of democracy," Ebenezer's senior pastor, the Rev. Raphael Warnock, told the congregation.
Outside Ebenezer, hundreds gathered to watch the service on a large screen outside the church. Some sang the gospel song "We Shall Overcome."
When Lewis was 15, he heard King's sermons on WRMA, a radio station in Montgomery, Alabama, he recalled in an interview for the Southern Oral History Program.
"Later I saw him on many occasions in Nashville while I was in school between 1958 and '61," Lewis said. "In a sense, he was my leader."
King was "the person who, more than any other, continued to influence my life, who made me who I was," Lewis wrote in his 1998 autobiography, "Walking with the Wind."
By the summer of 1963, Lewis was addressing thousands of people during the March on Washington, where King gave his "I Have a Dream" speech. He spoke then about Black people beaten by police and jailed - themes that resonate vividly in today's times.
"My friends, let us not forget that we are involved in a serious social revolution," Lewis told the huge crowd on the Washington Mall.
"To those who have said, 'Be patient and wait,' we have long said that we cannot be patient," he added. "We do not want our freedom gradually, but we want to be free now! We are tired. We are tired of being beaten by policemen. We are tired of seeing our people locked up in jail over and over again."
In 1965, Lewis was beaten by Alabama state troopers in the city of Selma in what became known as "Bloody Sunday."
Last Sunday, his casket was carried across the Edmund Pettus Bridge in Selma. The wagon rolled over a carpet of rose petals on the bridge that spans the Alabama River. On the south side of the bridge, where Lewis was attacked by the law officers, family members placed red roses that the carriage rolled over, marking the spot where Lewis spilled his blood and suffered a head injury.
Lewis was later awarded the Medal of Freedom by the nation's first Black president in 2011.
He spent more than three decades in Congress, and his district included most of Atlanta.
Shortly before he died, Lewis wrote an essay for The New York Times and asked that it be published on the day of his funeral. In the piece published Thursday, Lewis recalled the teachings of King:
"He said we are all complicit when we tolerate injustice," Lewis wrote. "He said it is not enough to say it will get better by and by. He said each of us has a moral obligation to stand up, speak up and speak out."
"Though I may not be here with you, I urge you to answer the highest calling of your heart and stand up for what you truly believe," Lewis added. "In my life I have done all I can to demonstrate that the way of peace, the way of love and nonviolence is the more excellent way. Now it is your turn to let freedom ring."
Former President Bill Clinton referenced the essay during his remarks Thursday: "It is so fitting on the day of his service, he leaves us his marching orders: Keep moving."