The attempted armed robbery happened around 2:30 p.m in a busy parking lot of a Randall's store on Fry Road.
Detectives believe the suspects were "juggers," who followed the couple from a bank across the street.
The couple went grocery shopping and were about to load the groceries in their SUV when a black Cadillac SUV pulled into a parking space in front of them.
An investigator said one man pulled out a gun and demanded the woman's purse.
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Her husband was on the other side of the car, and pulled out his weapon. Moments later, shots were exchanged.
On the Fry Road Shooting: 2-3 males attempted to rob a female. Her husband was able to retrieve a pistol & shoot at the males, striking at least one. That male is in the hospital being treated.— Ed Gonzalez (@SheriffEd_HCSO) December 29, 2018
The husband fired four rounds, hitting both men, according to deputies.
The suspects got into the getaway car and pulled onto Fry Road, where the vehicle crashed out, leaving two men to run off on foot.
The driver, who was hit in the shoulder ran to a nearby fire station for help, and collapsed.
He was transported to the hospital and treated.
His partner remains at large.
Fry Road Shooting: Another male, described as black male, 5’4”, late teens-early 20s, fled the scene. Unknown if he’s injured. Shooter remained at the scene and is cooperating with the @HCSOTexas investigation.— Ed Gonzalez (@SheriffEd_HCSO) December 29, 2018