At 3:19 a.m., officers responded to the intersection of Blossom Hill Road and Union Avenue, where they found a car that had driven off the roadway and into a tree, Los Gatos-Monte Sereno police Sgt. Kerry Harris said.
The driver was killed in the crash, and Harris said there were no passengers in the vehicle.
A number of streets remain closed while police are investigating the crash: Blossom Hill Road between Leigh Avenue and Blossom Dale Drive is closed, as well as the portion of Union Ave between Anne Avenue and Blossom Hill Drive, Harris said.
Police have yet to rule out alcohol as a factor in the crash.