It was quite a lineup with laughs from Jay Leno and music from Alanis Morissette. They played to a sellout crowd and raised $5 million for a new children's hospital.
"I like to tell jokes and it's fun, and people say, 'If you go here and you tell these jokes, you'll raise all this money.' Well, it's not really hard work," said Leno.
"It's a great cause, it is easy to see why these celebrities are so supportive, but their generosity is overwhelming," said Marc Benioff from Salesforce.com.
Benioff donated $100 million to build the children's hospital. Little 4-year-old Grace Rego of Piedmont was diagnosed with severe scoliosis and may have had to wear a brace for 10 years, but a UCSF doctor had something innovative.
"He performed this staple surgery on her back to avoid her having to wear a brace. Yeah there is not a lot of research that on a child her age it even works," said Grace's mother.
Her surgery was just five weeks ago and now Grace is doing very well.
"I like to play with my friends," said Grace.
It's a hospital focused on the latest medical research that can make a difference in people's lives. The new building is already under construction at Mission Bay. Part of the $ 5 billion medical campus. When it opens in 2014, they tell us it will be the most advanced children's hospital in the country. And Leno might be back for that, he has pull now. Mayor Ed Lee declared this Jay Leno Day in San Francisco.
"I feel short of short changed. There are only four hours left in the day," said Leno.
Lee told Leno he could come back here anytime and he can park one of his vintage cars in San Francisco for free up to four hours.
In the past two years, $8 million has been raised by this event.