Joseph Escobedo, Joel Vega-Araiza and Allan Diaz, all in their 20s, are accused of sexually assaulting a 14-year-old girl.
San Jose police say it happened during a house party at Escobedo's house over the weekend.
No one was home Tuesday, but signs of the party were still on the front porch.
More than a dozen people were at the house Saturday night, including the 14-year-old victim.
"She could have been an acquaintance of some sort or knew the people throwing the party through other friends," San Jose Police Department spokesperson, Sergeant Ronnie Lopez said. "The 14-year-old was intoxicated.
Police now think more people, in addition to the three suspects, may have also attacker her.
"It's a violent assault, it's a case that we look at extremely seriously as we would in any other type of allegations and what's important for us is to really put pieces of the puzzle together," Lopez said.
The victim left the party sometime after midnight Sunday morning. She went home and a short time later, a relative brought her to Santa Theresa Hospital in South San Jose.
Hospital personnel called police.
All of the suspect's neighbors knew about the party, but not what Escobedo is accused of.
"It doesn't matter what age, a woman getting sexually assaulted at any age is just horrible," neighbor Trung Nguyen said.
San Jose police hope more witnesses will come forward with information.
If you have any information regarding this case, please contact:
Crime Stoppers San Jose
SJPD - 408-277-4290