Michael Bush rushed for 109 yards and a touchdown for the Raiders (6-4), who suffered a scare when receiver Darrius Heyward-Bey was carted off the field with a neck injury in the fourth quarter.
Heyward-Bey was injured when linebacker E.J. Henderson's knee inadvertently hit him in the back of the head while he was being tackled. No movement could be seen in his extremities and there was no immediate word on his status.
Adrian Peterson left the game in the second quarter with an injured left ankle and the Vikings (2-8) weren't able to complete a fourth-quarter rally.