A two-door Toyota Solara crashed on state Highway 4 near Alhambra Avenue at about 1 a.m., according to the CHP.
The vehicle's two occupants were injured in the crash. The driver was transported by ambulance to Highland Hospital in Oakland and the passenger was transported by helicopter to a hospital in Fairfield, according to the CHP.
The pursuit began when officers attempted to pull over the driver of the vehicle for driving recklessly.