Police were dispatched around 11:45 a.m. to a call for a welfare check at an apartment in the 1100 block of Addison Street, according to Berkeley police spokeswoman Jennifer Coats.
Officers arrived at the home and discovered the body of a man in his 50s, Coats said.
His name has not yet been released.
Police said the subsequent investigation into the man's death determined that it was a homicide.
The investigation into the killing is ongoing and no suspect information was available.
Anyone with information about this case is asked to call Berkeley police at (510) 981-5741. Those wishing to remain anonymous may call Bay Area Crime Stoppers at (800) 222-TIPS.