Police say they issued a statewide AMBER Alert Saturday after Enrique Felix and Rose Chairez, both 28, kidnapped their four children -- 5-year-old Justin Felix, 7-year-old Enrique Felix, and 1-year-old twin girls Veronica Felix and Janeth Felix.
According to police, the children were in protective custody with their grandmother because their father was physically abusive.
Los Angeles Police Officer Sally Madera says that while detectives are actively working the case, "as of right now, unfortunately, there have been no leads." She encouraged the public to contact police with any tips.
Police say the suspects fled in a dark-colored, possibly gray or purple PT Cruiser with paper license plates, tinted windows, and a missing right-rear hubcap.
Enrique Felix is described as a male Hispanic with black hair, brown eyes, standing 5 feet 10 inches tall, and weighing around 220 pounds.
Rosa Chairez is described as a female Hispanic with red hair and brown eyes, standing 5 feet 2 inches tall, and weighing around 150 pounds.
Janet and Veronica are described as having black hair, brown eyes, standing 2 feet tall, and weighing approximately 20 pounds.
Police say Justin Felix is described as having black hair, brown eyes, standing 3 feet tall, and weighing approximately 50 pounds.
To report possible sightings, call 911 or the Los Angeles Police Department at (323) 342-4101 or (877) ASK-LAPD.
(The Associated Press contributed to this report)