Richmond Parkway is closed between Pittsburg and Gertrude avenues.
Officers are asking people to use an alternate route and the closure is expected to cause significant traffic problems because many drivers use Richmond Parkway to get between Interstate Highway 580 and Interstate Highway 80 in Richmond.
The CHP is asking people in the area to avoid breathing in the smoke, close windows and set their AC to recirculate.
Bay City News contributed to this report.
PHOTOS: Cars go up in flames at Richmond auto wrecking yard
Shelter in place in effect in Richmond at Gertrude Ave. bc of huge fire in a car junkyard. pic.twitter.com/xhibBS1UIi— Amy Hollyfield (@amyhollyfield) December 16, 2016